Genomics study finds shared disease pathways for humans and environmental test organisms

Chemicals toxic to humans may be picked up by tests on environmental model species, thanks to shared disease pathways, according to work part-funded by the EU’s PrecisionTox project. The work “blurs the line” between human toxicology and ecotoxicology and paves the way to “species-agnostic” adverse outcome pathways (AOPs), said lead author John Colbourne from the University of Birmingham, UK.